- HWN....browse for free, get verified to super communicate!
- HWN....No.1 E-platform for Healthcare professionals and the public!
- HWN....uniting and empowering healthcare professionals and the entire populace
- ..in a unique and systematic manner, through networking, couching and funding!
- HWN....empowering healthcare professionals and the entire populace!
- HWN....enlightening the general populace on health issues!
HWN Jobs
- CORPER JOBS AT BUENA SANTE PHARMACY
- INSTITUTE OF HUMAN VIROLOGY (21 POSITIONS) JOBS
- JHPIEGO (AUGUST) JOBS
- MAGODO SPECIALIST HOSPITAL LIMITED (9 SLOTS) JOBS
- PHARMACEUTICAL MARKETING COMPANY (MR) JOBS
HWN Blogs
- Classical heart healthy foods on HWN BLOGS
- Classical Warning Signs When The Human Liver Begins To Fail on HWN BLOGS
- Myths About Hygiene, Soaps, Germs, Sweat and Smell on HWN BLOGS
- Hernia does not heal on its own on HWN BLOGS
- Classical Essential Oils That Improves Focus Cum Memory on HWN BLOGS
news - Harmful effects of a cancer drug that can be alleviated on HWN CANCERS back to all News
Harmful effects of a cancer drug that can be alleviated on HWN CANCERS
Researchers at the Wihuri Research Institute and the University of Helsinki, Finland, have found that some of the harmful effects of a commonly used cancer drug can be alleviated by using gene therapy that stimulates blood vessel growth in the heart.
Doxorubicin treatment, which is commonly used in a variety of cancers, leads to cardiac atrophy and body wasting. The researchers found that in mouse heart, doxorubicin leads to blood vessel rarefaction, which was prevented by treatment with gene therapy using the VEGF-B growth factor.
As advances in cancer treatment have decreased deaths from cancer, doxorubicin-induced heart problems have become an increasing problem. The new findings give hope that in future the heart could be protected by gene therapy, allowing more thorough cytostatic cancer treatment. "Thus, the cancer itself would be treated more effectively and the adverse effects could be avoided, explains Markus Räsänen, MD, who made the discovery during his thesis studies.
Doxorubicin, a cytostatic agent of the anthracycline class, that was used in this study has been a target of intensive research in the scientific world for a long time, and its role has been described in thousands of research articles. This research article is the first one, where blood vessel-directed therapy has a clear protective effect against the doxorubicin toxicity, says Dr. Riikka Kivelä, who supervised the study.
Our findings show, that especially the endothelial cells, which form the inner surface of the vessels in the heart, have an essential role in the protection against the cardiotoxicity. More preclinical studies are needed though for the development of VEGF-B gene therapy for cardiac protection in patients" elaborates Räsänen.
Source: PNAS, HWN AFRICA.
: 2016-11-01 16:54:32 | : 1557
HWN News
- First Polish infant to survive on extreme dialysis on HWN MEDICAL MIRACLES
- Drug resistant tuberculosis end game on HWN INSIGHTS
- Too many women opting for caesarean sections (CS) to give birth on HWN SEX EDU
- The intelligent, strong and fearless Nurse that conquered Ebola on HWN ARCHIVE
- Medhi Benatia, down with injury on HWN SPORTS